Membranes, Free Full-Text
Por um escritor misterioso
Last updated 16 junho 2024
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Synapse structures, including neuronal and immunological synapses, can be seen as the plasma membrane contact sites between two individual cells where information is transmitted from one cell to the other. The distance between the two plasma membranes is only a few tens of nanometers, but these areas are densely populated with functionally different proteins, including adhesion proteins, receptors, and transporters. The narrow space between the two plasma membranes has been a barrier for resolving the synaptic architecture due to the diffraction limit in conventional microscopy (~250 nm). Various advanced super-resolution microscopy techniques, such as stimulated emission depletion (STED), structured illumination microscopy (SIM), and single-molecule localization microscopy (SMLM), bypass the diffraction limit and provide a sub-diffraction-limit resolving power, ranging from 10 to 100 nm. The studies using super-resolution microscopy have revealed unprecedented details of the nanoscopic organization and dynamics of synaptic molecules. In general, most synaptic proteins appear to be heterogeneously distributed and form nanodomains at the membranes. These nanodomains are dynamic functional units, playing important roles in mediating signal transmission through synapses. Herein, we discuss our current knowledge on the super-resolution nanoscopic architecture of synapses and their functional implications, with a particular focus on the neuronal synapses and immune synapses.
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Lipid Organization of the Plasma Membrane
![Membranes, Free Full-Text](https://iiif.elifesciences.org/lax/74773%2Felife-74773-fig1-v2.tif/full/1500,/0/default.jpg)
Identification of electroporation sites in the complex lipid
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SRNF membranes for edible oil purification: Introducing free
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Table Pe Lavel Mili Hd Song - Colaboratory
![Membranes, Free Full-Text](https://conductscience.com/wp-content/uploads/2021/10/membranes.png)
Biological Membrane: Definition, Structure, Components, and Functions
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Annexins induce curvature on free-edge membranes displaying
![Membranes, Free Full-Text](https://www.pnas.org/cms/10.1073/pnas.2218610120/asset/3e182d49-ae42-4666-84dc-3c4810621289/assets/images/large/pnas.2218610120fig01.jpg)
Engineering transmembrane signal transduction in synthetic
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Functional properties of cell-free expressed human endothelin A
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Fluid mosaic model - Wikipedia
Photoelectric signals generated by bovine rod outer segment disk
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Antibodies, Free Full-Text
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